Current Openings

Here are our current job openings. Please click on the job title for more information, and apply from that page if you are interested.

Use this form to perform another job search

The system cannot access your location for 1 of 2 reasons:
  1. Permission to access your location has been denied. Please reload the page and allow the browser to access your location information.
  2. Your location information has yet to be received. Please wait a moment then hit [Search] again.
Click column header to sort

Search Results Page 3 of 5

Dr. Xinwei Cao is seeking a Scientist/Lead Researcher for her lab in the Department of Developmental Neurobiology at St. Jude Children’s Research Hospital.   The Cao lab studies the molecular and cellular mechanisms that regulate the development of the vertebrate nervous system, with a special focus on the fundamental mechanisms governing the properties and functions of neural stem/progenitor cells. The Cao lab also investigates the molecular mechanisms and biological relevance of hypertranscription, a poorly understood phenomenon that involves a coordinated increase in the expression of the majority of the transcriptome.      As one of the premier pediatric diseases research institutes in the world, St. Jude Children’s Research Hospital provides exceptional resources and a supportive environment for career development.   Competitive candidates should have a strong background in developmental biology and molecular biology and experience in molecular, cellular, biochemical, imaging, and/or computational techniques. Recent publication in relevant journals is required.
Job ID
48047
Department
Developmental Neurobiology
Company
St. Jude Children's Research Hospital
Type
Full Time
We are seeking an outstanding and highly motivated Senior Researcher to join the laboratory of Dr. Mitchell Weiss, chair of the Department of Hematology at St. Jude Children’s Research Hospital.   The Weiss lab is particularly interested in non-malignant disorders of the hematopoietic system including β-thalassemia and sickle cell disease. Our research involves defining the mechanisms of gene regulation during hematopoiesis, the functions of non-coding RNAs, and the mechanisms of protein quality control such as autophagy and ubiquitin-mediated proteolysis in red blood cell formation and associated diseases. Moreover, we are developing novel genome editing based strategies to explore new therapies for β-thalassemia and sickle cell disease using Cas9 genome editing, base editing and other technologies.     We care deeply about the success of our lab members. We are also highly supportive of candidates who wish to pursue a PhD in the future.During his career at Harvard, University of Pennsylvania and St. Jude Children’s Research Hospital, Dr. Weiss has trained numerous students and post-doctoral fellows, most of who have gone on to successful careers in academia or industry.   The successful applicant will be experienced and conversant in a range of experimental approaches including mammalian cell cultures, animal experimentation and basic biochemical tools. Proficiency in in vivo [mouse] husbandry and manipulation is strongly preferred but not required.   Please include your CV and a cover letter (no more than 2 pages) If you have questions about the position, please do not hesitate to email Dr. Christakopoulos (gchrista@stjude.org) or Dr. Weiss (mitch.weiss@stjude.org).
Job ID
F1412
Department
Hematology
Company
St. Jude Children's Research Hospital
Type
Full Time
The Blanchard laboratory in the Department of Structural Biology at St. Jude Children’s Research Hospital is seeking a highly motivated Lead Researcher with experience in molecular biology, biochemistry and quantitative biophysical techniques. Our highly interdisciplinary, collaborative, mission-driven environment requires a creative team-oriented individual with strong leadership skills, who would ensure quality operations and our vision to successfully pursue scientific advances.     In this role, the successful candidate will use protein and/or nucleic acid biochemistry, including protein expression, purification, and labeling and/or nucleic acid manipulation and purification. Expert ability to distill, convey and present complex information in a clear and concise manner both verbally and in writing is essential, as well as passion to learn and navigate new research fields.
Job ID
48591
Department
Structural Biology
Company
St. Jude Children's Research Hospital
Type
Full Time
Our world-renowned Developmental Neurobiology department has an exciting employment opportunity for a Director of Behavior Core. In this role, you will have exposure to breakthrough behavior techniques and technologies, pertaining to modeling of neuropsychiatric diseases. This will involve conventional rodent behaviors combined with optogenetics, chemogenetics, telemetry, fiber photometry, and other state-of-the-art tools. Furthermore, the candidate will work closely with the departmental Neuroimaging Analysis Core, which assists in implementing machine learning for unbiased analysis of rodent behavior.   In this role, a candidate will be responsible for all aspects of rodent behavioral assays, including study design, programming software platforms, analyzing and interpreting data. This job will be specifically focused on developing, characterizing and validating standard and innovative behavioral studies. Previous extensive experience in rodent animal behavior models is required. Experience with behavioral software platforms such as MED-Associates and Clever Sys is highly preferred. The job requires adherence to quality control measures and scientific rigor for ensuring experimental consistency. Contributes to the scientific direction of the laboratory in partnership with Principal Investigator. Manages budget planning process. Provides direction and supervision to laboratory staff. Expected to maintain extensive knowledge and expertise in respective discipline. Responsible for the demands of multiple concurrent projects performed at the core in collaboration with our diverse faculty. Flexible work hours (including some weekends) will be required.  
Job ID
48640
Department
Developmental Neurobiology
Company
St. Jude Children's Research Hospital
Type
Full Time
St. Jude Children’s Research Hospital, a NCI designated comprehensive care center, is consistently ranked on Fortune Magazine’s “100 Best Places to Work For” list. Because at our world-class pediatric research hospital, every one of our professionals shares our commitment to make a difference in the lives of the children we serve.   The Human Applications (Cellular Therapy) Laboratory supports the Department of Bone Marrow Transplantation and Cellular Therapy by providing products for patients enrolled in investigator-initiated clinical research protocols. The laboratory supports many treatment trials for cancer and genetic diseases, using primary hematopoietic graft products and genetically modified products for sickle cell disease and CAR T-Cell therapy applications. The Human Applications Laboratory is composed of two sections, the Quality Control Section providing product analysis by flow cytometry and product quality testing for sterility, and the Stem Cell Processing Section providing cellular therapy product processing in accordance with good tissue practices and good manufacturing practices.     Contributing to our mission of finding cures and saving children, we are looking for an enthusiastic and dedicated professional to join the Stem Cell Processing Section as a Specialist I. The successful candidate will be responsible for performing complex, highly specialized technical processing procedures, using aseptic technique and maintaining attention to detail for technical and documentation functions.Cellular therapy processing experience is preferred. Essential computer skills, such as Word, Excel and Outlook as well as flexibility, teamwork, and good communication skills are required for this position. Additional requirements: Ability to work in teams and effectively communicate transitions in work processes. Excellent mathematical skill, analytical skill, and technical dexterity. Ability to function in a cleanroom environment and sustain prolonged physical exertion. Routine schedule is Monday through Friday with flexibility in shift hours as needed for processing procedures. (Rotates On-Call Coverage approximately every 6 weeks.)
Job ID
48717
Department
Human Applications Lab
Company
St. Jude Children's Research Hospital
Type
Full Time
We are seeking a highly motivated and creative Lead Bioinformatics Analyst to join the team of Dr. Kim Nichols in the Division of Cancer Predisposition at St. Jude Children's Research Hospital. As a Lead Bioinformatics Analyst your responsibilities will involve running existing genetics pipelines and developing new, faster and more efficient pipelines to support projects in cancer genetics and functional genomics. You will have ample opportunities to engage in research studies focusing on known hereditary forms of childhood cancer and discovery of new causes for familial cancers. You will be highly integrated into many existing and future collaborative projects within and outside of St. Jude which will allow for educational and cross-training opportunities.   You will work closely with research team members to analyze large-scale genomic datasets including WES, WGS, bulk and single cell RNA-seq, Cut&Run and ATAC-seq data, to identify novel cancer predisposing germline variants and interrogate the impacts of these variants on downstream gene function. You will develop, improve, modify, and operate data analysis pipelines, generate and provide analysis results and reports, and perform requested custom analyses.   The Department provides a highly interactive environment with collaborative opportunities, access to high performance computing clusters, a cloud computing environment, innovative visualization tools, highly automated analytical pipelines and mentorship from scientists with interests experience in data analysis, data management and delivery of high-quality results. The Division of Cancer Predisposition supports strong teamwork as well as individual and personal growth.   Candidates with a strong background and interest in genetics, cancer biology, and experience with use of genetic approaches to understand disease pathogenesis are highly encouraged to apply for this position. Familiarity with the analysis of large-scale cancer genomic datasets for germline as well as somatic mutations is preferred. This position is located in Memphis, TN, and relocation assistance is available.
Job ID
47904
Department
Oncology
Company
St. Jude Children's Research Hospital
Type
Full Time
The Velasquez laboratory in the Bone Marrow Transplant and Cellular Therapy Department is looking for a driven and creative scientist/lead researcher to join the team. We develop cell-based immunotherapies for high-risk leukemias with a strong focus on antigen discovery, bispecific CAR design and studying mechanistic implications of CAR T cell therapies. Our group provides a supportive environment, surrounded by an enthusiastic group of researchers and access to top-of the line resources.   This exciting opportunity will allow you to become part of a collaborative environment and develop and characterize novel immune-based therapies in project with high potential for translation into clinical trials.    Preferred skills: - The applicant must be able to conduct independent research in molecular biology, immunology and/or cellular therapy - Experience in molecular assays and tissue culture techniques.  - Experience performing multicolor flow cytometry  - Experience conducting in vivo experiments is highly desirable.  - Ability to communicate effectively - Excellent multi-tasking skills - Ability to work as part of a team - Eager to learn and implement new techniques. In addition to performing independent research, the applicant will also collaborate with other laboratory members on other endeavors.
Job ID
48243
Department
Bone Marrow Trans & Cell Thrpy
Company
St. Jude Children's Research Hospital
Type
Full Time
At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted from a lack of resources. At St. Jude, you will be part of a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.   This is an exciting opportunity for a researcher to join our Center for Advanced Genome Engineering (CAGE). The Shondra Pruett-Miller laboratory offers a strong team-based environment where you will work collaboratively with other investigators across the institution to support their research needs and develop and improve genome engineering technologies. As a member of our laboratory, you will also bring in cutting edge protocols to provide newer and better workflows to our genome engineering operations.   Successful candidates should display competencies in the following areas: - Understanding of and experience with molecular biology - Extensive experience with cell culture (experience with iPSC, ESC, of HSCs a plus) - Excellent verbal and written communication skills - Excellent multi-tasking skills - Ability to work as part of a team
Job ID
F1393
Department
Cell and Molecular Biology
Company
St. Jude Children's Research Hospital
Type
Full Time
The Department of Epidemiology and Cancer Control housed at St Jude Children’s Research Hospital in Memphis, Tennessee, is seeking applicants for a full-time mobile Health (mHealth) Research Scientist position for a National Cancer Institute-funded project. The candidate will work with senior faculty members, a project coordinator, Clinical Research Associates, and other researchers to improve health outcomes for aging childhood cancer survivors. The scientist will collaborate with an experienced health informatics/IT team to develop, deploy, and maintain mHealth platforms for collecting patient-reported outcomes and digital health markers for research. Under the supervision of lead faculty members, the candidate will be engaged in a variety of research activities related to conducting literature review, data collection and analysis, creating training materials for patient engagement, writing research papers, engaging in mHealth-enabled health interventions, and grant preparations.  
Job ID
48304
Department
Epidemiology & Cancer Control
Company
St. Jude Children's Research Hospital
Type
Full Time
The role of Supervisor- Animal Services contributes to developing treatments for diseases and new methods of diagnosis that fall in line with the St. Jude Children's Research Hospital's mission statement "Finding Cures. Saving Lives."  This role will directly provide supervisory and ancillary support within husbandry operations as well as other related duties assigned to meet the goals and objectives of the Animal Resource Center.     Work Schedule: Monday - Friday 7:00 am until 3:30 pm; Rotating 24 hour on-call weekend and holiday duty.
Job ID
48407
Department
ARC
Company
St. Jude Children's Research Hospital
Type
Full Time
The Histology and Tissue Processing Core located in the Center for Pediatric Neurological Disease Research (CPNDR) is seeking support staff (at the Researcher/Senior Researcher level). This individual will provide institution-wide service in the Center Without Walls (CWW), a component of the St Jude Pediatric Translational Neuroscience Initiative (PTNI) which fosters collaborative neuroscience research across St. Jude.  The successful applicant will have experience with tissue processing and histology and general knowledge regarding animal physiology/neuroscience is an advantage.  Highly organized candidates with good communication skills are encouraged to apply.
Job ID
48607
Department
Ctr-Ped Neurological Dis Res
Company
St. Jude Children's Research Hospital
Type
Full Time
The Department of Hematology at St. Jude Children's Research Hospital is seeking a Lead Research for their Induced Pluripotent Stem Celll (IPSC) core facility. The selected candidate will have the opportunity to collaborate across the department on multiple projects through the maintenance, differenciation, charaterization, and validation of IPSC lines. Additional tasks will include expansion banking and quality control, providing support for researchers, collecting and analyzing data.    The successful candidate will be experienced in Molecular Biology techniques and tissue culture, with preference to those with experience in IPSCs. The ability to work efficiently, handle multiple projects, and communicate effectively with people at all levels within an organization will help you be successful in this role.
Job ID
48730
Department
Hematology
Company
St. Jude Children's Research Hospital
Type
Full Time
The Department of Bone Marrow Transplantation and Cellular Therapy is looking for a Data Scientist to help further the mission of St. Jude Children's Research Hospital. The Data Scientist role will have a direct impact on analytics needs of the entire BMTCT Program, utilizing state-of-the-art technologies. This position will be responsible for using data to unlock trends and key insights that are critical for the success of BMTCT operations. In this role, you will gain significant domain knowledge across administrative, clinical, research and basic science areas and help them make effective data based decisions. This is an opportunity to assist sPrincipal Investigators, BMT Faculty, clinicians, and Lab Director in developing presentations, charts and graphs to effectively communicate and illustrate results of key-findings, data analysis and data/science models as well as present them to customers including executive leadership teams. 
Job ID
48753
Department
Bone Marrow Trans & Cell Thrpy
Company
St. Jude Children's Research Hospital
Type
Full Time
The Department of Computational Biology is seeking a highly motivated Bioinformatician to develop and apply computational and systems biology approaches to dissect the molecular circuits that drive tumorigenesis, tumor immune-escape and drug resistance, and identifying novel immunotherapy targets, biomarkers and combination therapies (particularly with immunotherapy) for the treatment of pediatric cancers. This analyst/scientist will analyze and integrate high-throughput omics data, at bulk and single-cell levels, including transcriptomic, genomic, epigenomic, functional genomic, chemical genomic and proteomic data to model context-specific cellular/molecular networks and to identify actionable targets, biomarkers or compounds that could be translated into clinic for the development of precision medicine in pediatric cancer. The scientist will report to Dr. Jiyang Yu and will work closely with our collaborators in the departments of Immunology and Oncology for experiment design and data generation, and with our pipeline and visualization teams to explore novel analysis approaches for single-cell RNA-Seq, NGS-based RNAi/CRISPR screening, immune-profiling and proteomics data for molecular network inference and target identification.   Candidates with a strong interest in cancer immunotherapy, cancer precision medicine and expertise in oncology, immunology, computational biology, bioinformatics are encouraged to apply. The successful candidate will also have an opportunity to participate in research projects involved in the analysis of the cancer genome, epigenome, transcriptome or proteome. Experience with omics data analysis using R or Python and familiarity with linux/unix is required. Experience and knowledge in immunology and/or immuno-oncology is highly desirable. Expertise in systems biology, network biology, parallel computing, web development, visualization and databases is also highly desirable.   The Yu Lab provides a highly interactive environment with projects involving basic and clinical research collaborators, access to high performance computing clusters, cloud computing environment, innovative visualization tools, highly automated analytical pipelines and teamwork with scientists who have deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. This position is located in Memphis, TN, and relocation assistance is available.    
Job ID
44476
Department
Computational Biology
Company
St. Jude Children's Research Hospital
Type
Full Time
At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted from a lack of resources. At St. Jude, you will be part of a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.   Our world-renowned Developmental Neurobiology department has an exciting employment opportunity for a highly motivated Scientist who has a strong background and interest in mechanisms of brain development, neurodevelopmental disorders, or brain tumors to join the lab of Dr.Young-Goo Han.    Recently, we revealed a key pathway that expands neural stem/progenitor cells and promotes the expansion and folding of the neocortex, the center for superior human cognitive abilities, and are now studying underlying molecular and cellular mechanisms and how alterations in such mechanisms lead to neurodevelopmental disorders and brain tumors.     Our lab is highly collaborative and uses diverse complementary approaches including genetically modified animals, pluripotent stem cell culture, brain organoids, genome editing, high resolution imaging, single-cell sequencing, spatial transcriptomics, proteomics, and in utero surgeries. The successful candidates will have strong experience in molecular, biochemical, cellular, and histological analyses of cell culture and animal models.
Job ID
48172
Department
Developmental Neurobiology
Company
St. Jude Children's Research Hospital
Type
Full Time
At St. Jude Children’s Research Hospital, talented faculty and staff work together and with colleagues worldwide-to advance the research and treatment of pediatric cancer and other catastrophic diseases.   St. Jude is anticipating hiring a Scientist or Senior Scientist in the summer months. We are seeking outstanding, highly motivated, and creative candidates for scientist roles in the new Therapeutic Genome Engineering (TGEn) group that is part of a multidisciplinary team of scientists and clinical researchers to help advance genome editing strategies to treat sickle cell disease to a Phase 1 clinical trial. Our ongoing therapeutic pipeline is fueled by internal scientific discoveries academic collaborations. Come join TGEn to enGENEer concepts to cures.   You will have the opportunity to work with a talented interdisciplinary team of scientists to develop a cellular therapy with the goal of treating patients here at St. Jude Children’s Research Hospital and worldwide. The ideal candidate will have a combination of experience with genome editing and human hematopoietic stem cells.   You will have the opportunity to learn about and support new exciting projects such as: - Development and optimization of pre-clinical genome editing strategies to treat hemoglobinopathies and other hematological diseases. - Process development and IND-enabling studies (Pharm/Tox)     Apply today! A cover letter is highly recommended.
Job ID
F1390
Department
Hematology
Company
St. Jude Children's Research Hospital
The Center for Translational Immunology and Immunotherapy, a collaborative effort between the Departments of Immunology and Bone Marrow Transplantation & Cellular Therapy (BMTCT), has recently launched, with a focus on immune monitoring of new clinical trials, efforts to define and exploit productive anti-tumor immune responses, and characterization of immune competence during standard and experimental cancer treatments.     We are seeking a Scientist to join this exciting multidisciplinary effort. As a member of the Thomas Lab, under the supervision of Dr. Jeremy Chase Crawford, your research will support our comprehensive efforts to study anti-tumor immunity and develop novel, immune-based treatments while collaborating with scientists, clinicians, and bioinformaticians across the institution.   In addition to applying cutting-edge techniques (like single-cell and spatial transcriptomics) to patient samples, you will have opportunities to help develop novel molecular and cellular approaches, pushing the boundaries of current laboratory capabilities.     The ideal candidate will be highly motivated and detail-oriented with an interest in immunology and immunotherapy, and have excellent laboratory, data curation, and critical thinking skills.     Experience with flow cytometry, PCR, NGS library preparation, molecular cloning, and cell culture is preferred. Experience with single-cell genomics and/or spatial transcriptomics is beneficial but not required. Excellent communication and organization skills are required, as you will play a major role in coordinating research efforts among various labs within the institution. In addition, the ability to work as a team player and collaborate effectively is essential for this position. 
Job ID
48273
Department
Translational Immuno-Oncology
Company
St. Jude Children's Research Hospital
Type
Full Time
A Scientist or Lead Researcher position is currently available in the laboratory of Dr. Paul Northcott (https://www.stjude.org/research/labs/northcott-lab.html) in the Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN. The Northcott lab is internationally recognized for making seminal contributions to the understanding of the genomics and developmental biology of childhood brain tumors. We seek accomplished, self-motivated, efficient, and meticulously organized scientists with a strong background in primary sample processing for cutting edge next-generation sequencing, including single-cell/nuclei and liquid biopsy analyses.   Candidates should be able to perform and coordinate a wide range of laboratory research procedures and conduct complex support tasks and projects determined by our current research. Duties will include molecular, cellular, and biochemical analyses using methods such as single-cell/nuclei sequencing, ATAC-seq, ChIP-seq, CUT&RUN, and sample processing for translational genomic studies. Prior experience with primary tissue handling and FACS analysis are highly desirable. The position will involve interaction with other staff scientists, bioinformaticians, and trainees on large, multidisciplinary projects and presentation of scientific findings during regular working group meetings. Candidates should be able to communicate effectively and work both independently and as part of a team.   Preferred Skills Experience with handling and processing of primary tissues for DNA, RNA, and protein extractions, single-cell/nuclei sequencing, ATAC-seq, ChIP-seq, CUT&RUN, library preparation/QC analysis, and cell sorting by FACS is strongly preferred. Candidates with excellent communication and organizational skills are encouraged to apply.
Job ID
F1395
Department
Developmental Neurobiology
Company
St. Jude Children's Research Hospital
Type
Full Time
Why St. Jude?Precision therapies. Better vaccines. Healthier, happier survivors. We dream big, and build our research programs to match. The engine of discovery at St. Jude is powered by some of the most reputable minds in science and medicine, equipped with world-class resources and driven by the shared mission of advancing cures. We understand that fundamental science builds the foundation for clinical impact. We are committed to supporting hypothesis-driven and exploratory research that asks daring questions to drive innovation.To support this pursuit, we need a Director of Neuropsychology Research Operations to lead our team. For more on what's happening in neuropsychology and at St. Jude, please watch this lecture by our very own Kevin Krull, PhD, Faculty Member in Epidemiology & Cancer Control.  
Job ID
48517
Department
Epidemiology & Cancer Control
Company
St. Jude Children's Research Hospital
Type
Full Time
We are seeking a motivated scientist for assay development with special emphasis on flow cytometry and molecular diagnostic laboratory skills. In this role you will provide technical support for global development projects, including flow cytometry panel design, implementation and cross-validation experiments. The selected candidate will be able to develop adapted standard operating procedures for limited resource pathology labs. Experience with molecular diagnostics, including tissue storage, DNA/RNA extraction, library creation preferred. The successful candidate would also be able to provide assistance on small “proof of concept” projects to help decrease major diagnostic discrepancies, increase quality of FFPE samples, and develop low cost tools to aid in diagnosis. Travel required. Foreign language skills preferred. 
Job ID
48660
Department
Pathology
Company
St. Jude Children's Research Hospital
Type
Full Time

Stay connected

We're breaking new ground at St. Jude. Stay up-to-date on our latest news and career opportunities in the areas you're most interested in by becoming a St. Jude Careers Insider.

Search all St. Jude Jobs, including postdoctoral research fellowships, clinical fellowships and faculty appointments.