Lead Researcher in Structural Biology - Scott Blanchard Group

Job ID
Structural Biology
Scientific Research


The Blanchard laboratory in the Department of Structural Biology at St. Jude Children’s Research Hospital is seeking a highly motivated Lead Researcher with experience in molecular biology, biochemistry and quantitative biophysical techniques.

Our highly interdisciplinary, collaborative, mission-driven environment requires a creative team-oriented individual with strong leadership skills, who would ensure quality operations and our vision to successfully pursue scientific advances.



In this role, the successful candidate will use protein and/or nucleic acid biochemistry, including protein expression, purification, and labeling and/or nucleic acid manipulation and purification. Expert ability to distill, convey and present complex information in a clear and concise manner both verbally and in writing is essential, as well as passion to learn and navigate new research fields.


  • Assume supportive positions in one or more research directions to reveal the mechanistic underpinnings of clinically important biological systems, such as ribosome-catalyzed protein synthesis, membrane protein transport/signaling, and host-virus interactions, with a special emphasis on mammalian systems.
  • Collaborate with St. Jude’s Protein Technology Center, Center for Advanced Genome Engineering, as well as Cryo-EM, NMR and X-Ray Crystallography Centers.
  • Being agile in learning and utilizing the most appropriate assays to answer the biological question at hand.
  • Regularly present research plans and findings in a clear, concise manner to both general and specialized audiences.
  • Regularly participate in preparation of high-quality manuscripts of findings for publication.


Minimum Education

  • A Bachelor’s degree in life science or other physical science is required
  • Ph.D is preferred

Minimum Experience

  • Five (5) years of relevant, post-degree work experience is required with a Bachelor's degree
  • Two (2) years of relevant post-degree work experience is required with a Master's degree
  • No additional experience is required with a PHD


What We Offer

Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.


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Other Information

St. Jude is an Equal Opportunity Employer

No Search Firms:

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

COVID-19 vaccine:

St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.

Publication links:



Apply to be a part of the mission of St. Jude Children's Research Hospital: to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of our founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. 


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