Senior Researcher in Hematology - Mitch Weiss Lab

Job ID
Scientific Research


We are seeking an outstanding and highly motivated Senior Researcher to join the laboratory of Dr. Mitchell Weiss, chair of the Department of Hematology at St. Jude Children’s Research Hospital.


The Weiss lab is particularly interested in non-malignant disorders of the hematopoietic system including β-thalassemia and sickle cell disease. Our research involves defining the mechanisms of gene regulation during hematopoiesis, the functions of non-coding RNAs, and the mechanisms of protein quality control such as autophagy and ubiquitin-mediated proteolysis in red blood cell formation and associated diseases. Moreover, we are developing novel genome editing based strategies to explore new therapies for β-thalassemia and sickle cell disease using Cas9 genome editing, base editing and other technologies.



We care deeply about the success of our lab membersWe are also highly supportive of candidates who wish to pursue a PhD in the future. During his career at Harvard, University of Pennsylvania and St. Jude Children’s Research Hospital, Dr. Weiss has trained numerous students and post-doctoral fellows, most of who have gone on to successful careers in academia or industry.


The successful applicant will be experienced and conversant in a range of experimental approaches including mammalian cell cultures, animal experimentation and basic biochemical tools. Proficiency in in vivo [mouse] husbandry and manipulation is strongly preferred but not required.


Please include your CV and a cover letter (no more than 2 pages)

If you have questions about the position, please do not hesitate to email Dr. Christakopoulos ( or Dr. Weiss (


The Researcher is expected to have the following responsibilities:

  • Provide support for the laboratory by collecting and analyzing data.
  • Able to work effectively to keep deadlines and manage multiple projects in parallel.
  • Demonstrate meticulous attention to detail, excellent organizational skills, interpersonal communication, and the ability to test, evaluate, implement, and troubleshoot new technologies.


Minimum Education

  • Bachelor's degree in relevant scientific area, such as molecular and cell biology, genetics, or genomics (M.S. preferred) is required.

Minimum Experience

  • Two (2) years of relevant, post-degree work experience is required.
  • No experience is required with a Master's degree.
  • Laboratory animal experience is strongly preferred, including techniques such as intraperitoneal and intravenous injections in mice, monitoring of animal health, collecting tissue samples, performing anesthesia and necropsies.
  • Experience with mammalian cell cultures and ability to perform molecular biology work is preferred including techniques such as DNA and RNA extraction, PCR, qRT-PCR, western blotting, flow cytometry, and ELISA.

What We Offer

Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.


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Other Information

St. Jude is an Equal Opportunity Employer

No Search Firms:

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.


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