The Weiss lab is particularly interested in non-malignant disorders of the hematopoietic system including β-thalassemia and sickle cell disease. Our research involves defining the mechanisms of gene regulation during hematopoiesis, the functions of non-coding RNAs, and the mechanisms of protein quality control such as autophagy and ubiquitin-mediated proteolysis in red blood cell formation and associated diseases. Moreover, we are developing novel genome editing based strategies to explore new therapies for β-thalassemia and sickle cell disease using Cas9 genome editing, base editing and other technologies.
We care deeply about the success of our lab members.
The successful applicant will be experienced and conversant in a range of experimental approaches including mammalian cell cultures, animal experimentation and basic biochemical tools. Proficiency in in vivo [mouse] husbandry and manipulation is strongly preferred but not required.
The Researcher is expected to have the following responsibilities:
Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.