The Department of Epidemiology and Cancer Control at St. Jude Children’s Research Hospital is seeking a highly qualified and motivated Bioinformatics Analyst with a demonstrated expertise in computational and statistical genomics to study the genetic and biological mechanisms underlying long-term toxicities of cancer treatments among survivors of childhood cancer.
The successful candidate will have a strong background in statistical genetics/genomics, biostatistics, computational genomics, bioinformatics, or a related quantitative field, and strong programming skills, and should be excited to contribute to advancing the science and pharmacogenomics of treatment-related late effects in childhood cancer survivors. Research projects will involve creating pipelines and analyzing large-scale omics data including, but not limited to, whole genome and whole exome sequencing, RNA-seq, ATAC-seq, proteomics and metabolomics, in relation to the clinical phenotypes. Strong research experience in genome-wide association studies (GWAS) of common and rare variants (both NGS and chip-based genotype) data and eQTL mapping is required. Proficiency in statistical genetics/genomics software including PLINK, GATK, matrixeQTL, and at least one of more programming languages such as R, Python, Perl, Java, or C++ under Linux/Unix environment is required. Familiarity with large genetic databases such as the UK Biobank, 1000 Genomes Project, gnomAD and others is desired.
The department provides a highly interactive environment with collaborative opportunities, access to high performance computing clusters, a cloud computing environment, innovative visualization tools, highly automated analytical pipelines and mentorship from scientists with interests experience in data analysis, data management and delivery of high-quality results. The Department of Epidemiology and Cancer Control supports strong teamwork as well as individual and personal growth.
Please include a cover letter including responses to the required skills/qualifications.
Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.
As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.
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