Lead-Software Architect I

Job ID
Information Services
Info Technology
Job Location


St. Jude Children’s Research Hospital is hiring a Lead Software Architect I to build innovative high-performance image data management and visualization software systems in support of its basic research programs. The successful candidate is communicative and passionate about software architectures at the interface between image data science and software engineering; with demonstrated expertise in one or more of the following areas: full-stack software development, scientific data management, machine learning, large-scale scientific data analysis, computer graphics, NoSQL databases, and GPU and High Performance Computing  (HPC) technology. The successful candidate will work with, and further shape, a growing dynamic team with Dr. Khaled Khairy in St. Jude’s new Center for Bioimage Informatics. Experience in image processing, computer vision, and game development is a plus.


At St. Jude Children’s Research Hospital international teams of scientists address some of the most pressing questions in biology. This position is an opportunity to design and implement high-quality innovative open-source software systems that advance this basic research enterprise at the bleeding edge. Examples of projects supported by the Center for Bioimage Informatics include image restoration and reconstruction, animal trackers, virtual reality environments, real-time processing for emerging imaging technologies and high-content screens, machine learning on HPC and in the Cloud, and multi-dimensional data visualization.







Minimum Education

  • Bachelor's degree in quantitative science, computer science or other related fields

Minimum Experience

  • Seven (7) years of experience in information systems technology design and hands-on implementation including five (5) years of experience in the role of information systems and software Engineer
  • Experience in image processing, computer vision, and game development is a plus
  • Experience with collaborative  open-source software projects is a plus
  • Experience with full-stack software development and SaaS is a plus
  • Experience with High Performance Computing is preferred
  • Experience with Python, Java, and C++ is a plus
  • Experience with Unreal Engine and/or Unity Engine is a plus

Other Credentials

ITIL, SOA, or other enterprise architecture certification such as TOGAF 9 by the Open Group (TOGAR 9), Zachman Certified - Enterprise Architect (AZCHMAN), Professional Cloud Solutions Architect by Cloud Credential Council (CCC-PCSA), or Red Hat Certified Architect (RHCA) preferred

What We Offer


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Other Information

COVID-19 vaccine:


As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.


EEO Statement:  St. Jude is an Equal Opportunity Employer

No Search Firms:

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.



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