We are seeking a highly driven scientist with broad interest in protein kinases, to oversee, organize and coordinate the activities of multiple researchers in a dynamic, comprehensive, inter-disciplinary initiative at the Department of Structural Biology, St. Jude Children's Research Hospital.
The project will extend the ultra-high field NMR spectroscopy and biochemistry approaches developed recently by the Kalodimos lab (Science 370, eabc2754, 2020) to study the human kinome. This is a large-scale project that aims to detect and structurally characterize the distinct conformational states populated by kinases, and to dissect the mechanisms of allosteric regulation and those underpinning oncogenic and drug-resistance mutations. This strategy will be integrated with and complemented by data-science and computational approaches developed by the Babu lab (Nature 587, 650, 2020), to systematically characterize the conformational landscape of the human kinome.
We expect this initiative to have a profound impact on the field, transforming our understanding of protein kinases. We are looking for an enthusiastic scientist to join this project and take a key organizational role.
This is a high-level staff position, and the Prinicipal Scientist will:
Furthermore, the ideal candidate should have a track-record of exceptional organizational and problem-solving skills; outstanding communication skills; be able to absorb, synthesize and integrate different types of information; work independently; and thrive on a highly collaborative and fast-moving environment.
Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.
As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.
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