• Director-Precision Genomics

    Job ID
    Computational Biology
    Job Location
  • Overview

    The Department of Computational Biology is seeking a highly motivated Director of Precision Genomics to lead the genomics analysis of the institutional clinical genomics program. Reporting to the Chair of Computational Biology, the Director of Precision Genomics will supervise the clinical genomic analysis team to analyze clinical cases and to participate in relevant research initiatives.  In collaboration with the Departments of Pathology and Oncology, the Director will oversee continued development and implementation of clinical bioinformatics standard operating procedures for College of American Pathologists (CAP), Clinical Laboratory Improvement Amendments (CLIA) and state accreditation and certification. The Director will provide scientific consultation and training for software engineers, bioinformatics analysts/scientists, pathologists, and oncologists involved in the clinical genomics program. The Director will coordinate with stakeholders in legal, clinical, and research departments to ensure delivery of the clinical genomic data for institutional research use and public data sharing.


    The clinical genomic analysis team at St. Jude performs the state-of-art innovative analysis aiming to set the standards for precision oncology practice in pediatric cancer. An integrated 3-platform sequencing of whole-genome, whole-exome and RNA-seq has been implemented since 2013 delivering clinical-relevant findings and making high-profile discoveries that impact patient care. Our clinical genomics program is a multidisciplinary teamwork involving pathologists, oncologists, and genetic counselors, as well as genomic analysts and software engineers at the Department of Computational Biology. Since 2019, clinical genome sequencing data has been available to the biomedical research community in real-time on St. Jude Cloud, the world’s largest public repository of pediatric genomics data.



    The department of Computational Biology is a highly interactive environment with projects involving basic and clinical research collaborators, access to high performance computing clusters, cloud computing environment, innovative visualization tools, highly automated analytical pipelines and teamwork with scientists who have deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. This position is located in Memphis, TN, and relocation assistance is available.



    Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.

    Minimum Education

    • PhD in Bioinformatics, Molecular Biology, Biochemistry, Genetics, Computer Science or related field required.

    Minimum Experience

    • Six (6) years of experience post PhD in the area of cancer genomics. High-impact publications and experience in cancer genomics research programs and/or international/national professionally related organizations are required
    • Experience with at least one programming language is required.
    • Experience with next-generation sequencing data analysis methods including variant detection and gene expression is required.
    • Experience in clinical or medical research is preferred.

    Other Credentials

    • Certification of American College of Medical Genetics and Genomics (ACMGG) certification is preferred.

    EEO Statement

    St. Jude is an Equal Opportunity Employer







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