• Clinical Genome Analyst /Genetic Variant Curator

    Job ID
    Computational Biology
    Job Location
  • Overview

    St. Jude Children’s Research Hospital is seeking a Clinical Genome Analyst/Genetic Variant Curator who is excited to join our Clinical Cancer Genomics team. As a Clinical Genome Analyst, you will curate and mine whole-genome, whole-exome and transcriptome sequencing data and also create and validate new computational methods to detect and classify somatic and germline genetic alterations in pediatric cancer patients. These methods will uncover genetic predispositions to cancer and allow us to match patients to targeted therapies and clinical trials. Clinical Genomics at St Jude is a collaborative project between the departments of Computational Biology, Pathology, and Heriditary Cancer Predisposition and the goal is to integrate clinical genomics into the continuum of care and improve patient outcomes.


    In this role you will form the vital connection between laboratory scientists and clinicians necessary to make precision oncology a reality by understanding both computational methods and the underlying biology. Our clinical genome analysts are part of a multidisciplinary team and will work closely with pathologists, oncologists and genetic counselors. You also work closely with our bioinformatics pipeline and visualization teams to explore novel analysis approaches that aid molecular classification and clinical reporting, contribute ideas to automate and improve existing analysis methods. The analyst will also have the opportunity to participate in research projects and lead and assist in preparing and submitting manuscripts. 


    The clinical genome analysis team works closely with our pipeline, web and cloud teams. The St. Jude Cloud is the world’s largest public repository of pediatric cancer genomics data on a cloud computing platform designed to be fast and easy to use. The department of Computational Biology provides access to high performance computing clusters, cloud computing environment, innovative visualization tools, highly automated analytical pipelines and mentorship from faculty scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects.





    Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “100 Best Places to Work” list and is exceptionally positively reviewed on GlassDoor.

    Minimum Education

    • Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required

    Minimum Experience

    • Ph.D which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software); OR If Ph.D with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required
    • Experience with programming languages such as Perl, C, or Java required.

    EEO Statement

    St. Jude is an Equal Opportunity Employer






    No Search Firms:

    St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.


    Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
    Share on your newsfeed

    Stay connected

    We're breaking new ground at St. Jude. Stay up-to-date on our latest news and career opportunities in the areas you're most interested in by becoming a St. Jude Careers Insider.

    Search all St. Jude Jobs, including postdoctoral research fellowships, clinical fellowships and faculty appointments.